Tribrid

Tribrids are a cross-breed of three different supernatural species. The term is commonly used to describe a vampire-werewolf-witch tribrid due to the fact that they were the first supernatural tribrid to be introduced in the series.

Tribrids possess both the strengths and some of the weaknesses of their parent races, along with powerful attributes unique to themselves alone due to their combined heritage. For vampire-werewolf-witch tribrids, this includes  being able to transform into a wolf without the Full Moon's influence.

Powers.

 * Werewolf Gene: Being part werewolf, tribrid's bodies contains the werewolf gene that provides them, with standard werewolf attributes provides them with enhanced senses, such as hearing, sight, and smell, as well as heightened aggression. The three tribrids are not bound to the moon to transform into a werewolf.
 * Vampire Gene: Being part vampire, tribrid's bodies produces vampire blood which is constantly running through their system, tainted with dark magic.
 * Enhanced Healing Factor: Tribrid's can heal from injuries with a speed comparable to normal vampires. Their blood also retains the vampiric ability to heal others as Hope, Nick, and Finn were able to heal their mother's while in the womb.
 * Siring: Tribrid's blood has the ability to turn werewolves and witches into hybrids as long as they first drink their blood during the transition.
 * Witch Gene: Being part witch, tribrid's can channel vast amounts of mystical energy. According to Dahlia, as a firstborn of her bloodline, Hope has the potential for great, but destructive magic.
 * Channeling: Tribrid's have the power to invoke extra forms of energy by focusing on external forces.
 * Potion Brewing: Tribrid's have the power to brew and concoct potions, remedies and elixirs that have supernatural properties.
 * Spell Casting: Tribrid's have the power to change and control events through the use of incantations and more.
 * Divination: Tribrid's have the power to divine future, past, and present events based off extrasensory perception.
 * Werewolf Bite Cure: Tribrid's blood is the only cure for a normal werewolf or a non-Original werewolf-vampire hybrid venom; this ability was inherited from Hope, Nick, and Finn's father; the Original hybrid, Niklaus. Like Klaus' blood, their blood cannot cure a bite from the Beast.

Weakness.

 * Disbelief: The act of denying or disbelieving in one's potential could cause tribrid's to inadvertently suppress their magical power.
 * Distraction: Denying tribrids from concentrating or giving full attention to their spells, may render them ineffective.
 * Emotions: Tribrid's magic is subject to the influence of their emotional state and may fluctuate according to them when untrained. According to Sheila Bennett, strong emotions such as worry and anger can fuel a witch's power while emotions such as fear may prevent a witch from properly accessing their powers.
 * Herbs: Ingestion of certain herbs can cause a witch to lose consciousness and prevent them from using magic for a undetermined amount of time. The Lobelia flower prevents concentration and the practice of magic and can be used to weaken a witch as one would weaken a vampire with vervain. Being part werewolf and vampire, they may also acquire the adverse effects of wolfsbane and vervain as well.
 * Huntress' Blood: Consumption of a supernatural huntress' blood will cause a witch to lose their ability to use magic. Prolong exposure poisons them, leading them to get sick and some brands will appear in their body and may eventually lead to death. According to Alex and Rayna Cruz, Rayna's blood can't be reversed for anything and all the attempts to make a cure were unsuccessful. It is unknown what effect Rayna's blood has on tribrids.
 * Magic: Tribrids are still susceptible to the powers of witchcraft. This is inclusive of mystical objects such as Papa Tunde's Blade, Hope's bracelet, and Dark Objects. A siphoner can siphon the magic from a witch where prolong exposure may lead to death.
 * Mortality: Despite their mystical attributes, tribrid's are still human and share many of the same weaknesses as non-supernatural beings (e.g. age, decapitation, disease, heart-failure, suffocation, snapped neck, etc.)
 * Overexertion: The excessive use of magic could lead to disorientation, nose bleeds, unconsciousness, and if taken to the extreme, death.
 * Unique Physiology: Being born with aspects of all three species, tribrid's nature are somewhat at odds with each other. Dahlia deduces that without proper guidance, Hope's potential as a firstborn of her family's bloodline will prove destructive and unstable when mingled with vampire blood and werewolf aggression.
 * Death: Having been born with vampire blood constantly produced in their systems, tribrid's have the potential for vampirism upon death.
 * Murder: Having been born with the werewolf gene, tribrid's have the potential for lycanthropy when they kills someone.

Known Types of Tribrid
Werewolf-Vampire-Witch; Hope, Nick and Finn.